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The brain stem is made up of the midbrain, pons, and medulla. Se hela listan på cancerwall.com (Pediatric) Diffuse Intrinsic Pons Glioma (DIPG) Molecular Pathogenesis, Immunology & Future Prospects 2. • Brainstem Gliomas – 10-20% of all CNS tumors in children – More common in children than adults • Diffuse Intrinsic Pontine Glioma • Leading cause of brain tumor–related death in children 58-75% of all brainstem tumors Khatua, et al. 2011. Se hela listan på royalmarsden.nhs.uk The term brain stem glioma is a generic description that refers to any tumor of glial origin arising in the brain stem, inclusive of the midbrain, pons, and medulla. While other histologies (e.g., ganglioglioma) can occur in the brain stem, the following two histologies predominate: Look up the Polish to English translation of glioma in the PONS online dictionary.

Pons glioma

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Diffuse intrinsic pontine glioma, or DIPG, is an aggressive brain tumor that forms in the base of the brain. DIPG begins in the brainstem, in an area called the pons.The pons controls vital life functions including balance, breathing, bladder control, heart rate, and blood pressure. Diffuse intrinsic pontine gliomas (DIPGs) are highly-aggressive and difficult-to-treat brain tumors found at the base of the brain. They are glial tumors, meaning they arise from the brain's glial tissue — tissue made up of cells that help support and protect the brain's neurons. Brainstem gliomas, especially those originating in the pons, are best appreciated on midline sagittal T2 images. Sagittal images demonstrate the pontine enlargement, undulating contour of the ventral surface of the pons, and mass effect on the fourth ventricle.

Pathological evaluation of DIPG describes a diffuse tumor of the pons, often infiltrating the medulla and midbrain, with otherwise typical characteristics of histopathological heterogeneous glial neoplasms.

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They are glial tumors, meaning they arise from the brain's glial tissue — tissue made up of cells that help support and protect the brain's neurons. Brainstem gliomas, especially those originating in the pons, are best appreciated on midline sagittal T2 images.

Pons glioma

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Pons glioma

Tumors in the pons are called pontine gliomas (or diffuse intrinsic pontine  Diffuse intrinsic pontine glioma (DIPG) is a leading cause of brain cancer-related death in children.

Pons glioma

This is a natural way to feel. Brainstem gliomas develop in the brain stem that connects the base of the brain to the spinal cord, just above the back of the neck. The brain stem consists of three parts: The midbrain, which develops into its stem form out of the middle of the brain.
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By pathology, this tumor is most often a fibrillary astrocytoma or its higher grade counterparts (anaplastic  Diffuse Intrinsic Pontine Glioma (DIPG) is a tumour located in the middle of the brain stem.

DIPG is a brainstem glioma. Gliomas that occur in the midbrain and medulla (the top and bottom segments of the brainstem, respectively) are usually low grade (grade I). However, those that arise in the pons (the mid-portion of the brainstem) are usually grade IV tumors and typically grow much faster and progress more rapidly. Diffuse intrinsic pontine gliomas (DIPG) are highly aggressive and difficult to treat brain tumors found at the base of the brain. They are glial tumors, meaning they arise from the brain's glial tissue — tissue made up of cells that help support and protect the brain's neurons.
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Diffust Pons Gliom – Funkisfeministen

Brain stem gliomas are more common in children than in adults. Reirradiation in patients with diffuse intrinsic pontine gliomas: The Canadian experience In this limited experience, rRT was safe and feasible in patients with progressive DIPG, providing neurological improvement and a prolonged life span in most patients.


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Diffus inneboende pontin gliom - Diffuse intrinsic pontine

Drawing of brain anatomy showing the brain stem ,  The term diffuse intrinsic pontine glioma is synonymous.